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The musculoskeletal system includes tissues that have remarkable regenerative capabilities. Bone and muscle sustain micro-damage throughout the lifetime, yet they continue to provide the body with the support that is needed for everyday activities. Our current understanding is that the regenerative capacity of the musculoskeletal system can be attributed to the mesenchymal stem/ stromal cells (MSCs)...
Pathology of the musculoskeletal system is widespread in the population and is one of the most common diseases in patients of older age groups. The most significant are osteoporosis, osteoarthritis, and sarcopenia. All three components separately, of course, lead to lower quality of life. We show the mechanisms of their interaction and their combined impact on the musculoskeletal system as a target...
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