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Background Germline mutations in the BRCA genes dramatically increase the risk of breast cancer. In the general population, breast cancer risk is affected by age at menarche, by age at first birth, by the number of births and by the duration of breast feeding. Whether this is true for mutation carriers is not clear. Methods In a case–control study, nested in a population-based cohort of the Icelandic...
Objectives To describe the design of the Million Women Study and the characteristics of the study population. Study design Population-based cohort study of women aged 50-64 in the UK. Setting Women are asked to join the Million Women Study when they are invited to routine screening for breast cancer at 61 of the screening centres of the UK National Health Service Breast Screening Programme (NHSBSP)...
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