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Chlorella vulgaris (C. vulgaris), a unicellular green microalgae, has been widely used as a food supplement. It was reported to have massive amount of antioxidants such as carotenoids, vitamins E & C and enriched with several minerals. However not many studies have evaluated the chemopreventive potential of this algae against cancers. The aim of our study was to vary culture condition of C. vulgaris...
All-trans retinoic acid (RA) as a useful therapeutic anti-cancer agent is known to induce apoptosis and growth inhibition of human breast cancer cells (MCF- 7 cells). Whereas insulin like growth factor-I (IGF-I) plays an important role in proliferation of cancer cells. RA dose- and time- dependency decreased in the level of secretion and synthesis of IGF-I. The treatment with 10' M RA for 72h significantly...
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