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Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in developed countries. It is a disease of the elderly, usually incurable and characterized by significant clinical and biological heterogeneity. Many patients are diagnosed after the incidental finding of a sustained lymphocytosis, while others present with symptomatic disease requiring treatment. Clinical features arise from immune...
Chronic lymphocytic leukaemia (CLL) is the commonest leukaemia in the Western world. It is a disease of the elderly and is usually incurable except in a minority of patients suitable for allogeneic haematopoietic stem cell transplantation. Many CLL patients are asymptomatic and the condition is diagnosed following the incidental finding of a sustained lymphocytosis. Clinical features arise as a result...
Kidney and upper urinary tract cancers account for approximately 54,000 cases every year in the United States, and represent about 3.7% of adult malignancies, with more than 13,000 annual deaths. Classification of renal tumors is typically based on histomorphologic characteristics but, on occasion, morphologic characteristics are not sufficient. Each of the most common histologic subtypes harbors...
Inflammatory breast carcinoma is a rare and aggressive form of breast cancer. It is rapid in onset and clinically mimics mastitis. We discuss a patient who came to our office with an apparent mastitis that was ultimately determined to be inflammatory breast carcinoma. A review of the typical clinical presentation, diagnostic imaging findings, biochemistry, treatment, and prognosis of the disease follows.
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