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Aims
To investigate the antidepressant role of oligodendrocyte‐derived exosomes (ODEXs)‐containing sirtuin 2 (SIRT2) and the underlying mechanism both in vivo and in vitro.
Methods
Oligodendrocyte‐derived exosomes isolated from mouse serum were administered to mice with chronic unpredictable mild stress (CUMS)‐induced depression via the tail vein. The antidepressant effects of ODEXs were assessed...