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Full lengths of right coronary artery obtained at autopsy and examined in hematoxylin and eosin stained paraffin sections sometimes reveal the presence of at least one instance of atheroma (YesA specimens). YesA specimens are nearly always those with generalized intimal fibroplasia, measured by excessive intimal thickness per smooth muscle cell. Accumulating evidence suggests that aging governs the...
Histologic features of arterial intima have been quantified at autopsy by morphometric methods in 66 individuals aged 6-30 years, in whom cardiovascular risk factors had been measured prospectively prior to death. Measures of serum cholesterol were found to correlate significantly with the extent of foam cell infiltration seen in paraffin sections and the intensity of lipid staining in frozen sections...
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