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Aging is associated with a loss of the ability to maintain homeostasis in response to physiologic and environmental disturbances. Age-related dysregulation of food intake and energy balance appears to be the result of impaired responsiveness of hypothalamic integrative circuitry to metabolic cues, which can lead to lack of appropriate food intake (the anorexia of aging) and thus to inappropriate weight...
McGREGOR I. S. AND A. M. LEE. Metabolic changes associated with ingestion of different macronutrients and different meal sizes in rats. PHYSIOL BEHAV 57(2) 277-286, 1995.--Indirect calorimetry was used to investigate whole-body metabolic changes occurring during and after feeding in the rat. Measurement of respiratory exchange allowed the derivation of respiratory quotient (RQ = CO 2 produced/O...
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