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Purpose We have previously demonstrated that prostate tumors that highly express Bcl-2 are not only more tumorigenic, but also more angiogenic than low Bcl-2 expressing tumors. Observed increased rates of angiogenesis are likely due to the secretion of multiple factors from the tumor cells. Experimental design Human endothelial cells were subjected to exogenous VEGF or conditioned media from PC-3...
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