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Introduction Biliopancreatic diversion and Gastric bypass are associated with a rapid improvement in insulin resistance few days after surgery. The purpose of this study was to evaluate the short-term effects in insulin resistance following sleeve gastrectomy (SG). Materials and methods Between December 2007 and September 2008, 17 consecutive obese type 2 diabetes mellitus patients (three men, mean...
Aims/hypothesis Sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) is involved in cellular stress responses linked to obesity and type 2 diabetes. We determined the role of SNARK in response to metabolic stress and insulin action on glucose and lipid metabolism in skeletal muscle. Methods Vastus lateralis skeletal muscle biopsies were obtained from normal glucose tolerant...
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