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We investigated whether innate differences in cytokine response were associated with the absence of osteoarthritis (OA) in old age.In 82 participants from a cross-sectional birth cohort, radiographs of hands, hips and knees were taken at the age of 90 years. OA was defined as a Kellgren–Lawrence score of at least two. “Free from OA” was defined at patient level as absence of hip and knee OA, and presence...
Cytokine production in synovial membranes (SM) and osteochondral fragments (OCF) may influence the development of equine osteoarthritis (OA). In this study, the presence of interleukin (IL)-6 and cytoplasmic and extracellular high mobility group box protein (HMGB)-1 in SM and osteochondral tissue from healthy and diseased equine joints was investigated by immunohistochemistry. Additionally, microscopic...
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