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Antihistamines are considered safe and used worldwide against allergy, pruritus, nausea, and cough and as sleeping aids. Nonetheless, a growing number of reports suggest that antihistamines also have immunoregulatory functions.We examined the extent and by what potential mechanisms histamine-1-receptor (H1R) antagonists exert immune suppressive effects.Immune suppression by antihistamines and immunosuppressants...
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