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Résumé: L'angiogénèse est un mécanisme central dans le processus de croissance tumorale et de métastases. La famille du VEGF et des récepteurs au VEGF est un des régulateurs les plus importants de l'angiogenèse. Différents agents ciblant la voie du VEGF et du VEGFR sont en cours d’étude à différentes phases de développement dans des tumeurs solides très diverses. Les inhibiteurs de tyrosine kinases...
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