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Obesity is associated with an array of adverse physiological, psychological, and social consequences. Tackling obesity remains difficult, given the challenges of maintaining positive behavior changes. Obesity occurs from persistent positive energy (excessive energy intake with insufficient counteractive energy expenditure), but several biological, psychological, and environmental factors influence...
Food intake is regulated by a complex interaction of central and peripheral pathways. A range of neuropeptides affects feeding either through actions at the gastrointestinal/hepatic level or in the central nervous system. Circulating signals such as leptin and insulin modulate and interact with these neuropeptide systems to control energy balance. The roles of the melanocortin MC4 receptor pathway,...
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