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Regularization of iterative reconstruction for fully dynamic PET has often been achieved implicitly by estimating coefficients relating to temporal basis functions, such as data-derived temporal basis functions, wavelet temporal basis functions, or compartmental model based temporal basis functions (direct kinetic parameter estimation). In this work, we propose and evaluate a method for anatomy-guided...
EM reconstructions with point-spread-function (PSF) modelling is performed to increase the spatial resolution in PET images. These images exhibit slower initial convergence compared to reconstructions without PSF modelling. Furthermore, they exhibit more pronounced ringing around the edges of sharp features. We investigate the effect of different objects and PSF modelling on the convergence rate and...
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