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Matricine, a genuine compound of chamomile, is unstable under acid conditions. Upon steam distillation it is readily converted into chamazulene carboxylic acid and further on into chamazulene. In the present work stability tests were performed in the pH-range between 4 and 10. The decomposition of matricine in aqueous pH adjusted and in buffered solutions was monitored using an isocratic HPLC-method...
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