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To characterize oxidative stress and metabolic activity in xenografted human ovarian tissue using microdialysis.Prospective experimental study.Gynecology research unit at a university hospital.Cryopreserved ovarian cortex from five women 27–35 years of age.Frozen-thawed human ovarian tissue fragments were xenografted to the back muscle of ten nude mice. Before grafting, a microdialysis probe was placed...
Permethrin (PER), the most frequently used synthetic Type I pyrethroid insecticide, is widely used in the world because of its high activity as an insecticide and its low mammalian toxicity. It was originally believed that PER exhibited low toxicity on untargeted animals. However, as its use became more extensive worldwide, increasing evidence suggested that PER might have a variety of toxic effects...
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