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The effects of l-carnosine (β-alanyl-l-histidine) on the neural activity of the renal sympathetic nerve and on DOCA-salt hypertension in rats were examined. Intravenous injection of 1 μg l-carnosine inhibited renal sympathetic nerve activity in urethane-anesthetized animals, and a diet containing 0.0001% or 0.001% l-carnosine decreased blood pressure elevation in DOCA-salt hypertensive rats. Since...
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