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Amphotericin B (AmB) is present as aggregates in aqueous media. Sodium deoxycholate (NaDC) is known to cause disaggregation of AmB and to form monomers, as is observed by the increase of absorbance at 414nm. By following the fluorescence intensity at 472nm (λ ex 335nm), it was found that with increasing NaDC concentration there is a progressive disaggregation of AmB leading to increase in...
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