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Three concomitant phenomena occur in the later years of childhood: increases in the incidence of asthma, obesity and early menarche. This article is an overview of the current epidemiologic, basic, genetic and epigenetic evidence about this relationship. As a consequence we propose that obese girls who have an early menarche (≤ 11 years of age) constitute a new asthma phenotype in childhood. Future...
To investigate the prevalence of polycystic ovary syndrome (PCOS) in adolescents and its association with obesity.Cross-sectional study using electronic medical records.Not applicable.Adolescents aged 15–19 years (n = 137,502).None.PCOS diagnosed or defined according to National Institutes of Health (NIH) criteria.The prevalence of a confirmed diagnosis of PCOS was 0.56%, which increased to 1.14%...
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