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In this study we sought to gain insights of the structural and mechanical heterogeneity of dentin at different length scales. We compared four distinct demineralization protocols with respect to their ability to expose the periodic pattern of dentin collagen. Additionally, we analyzed the phase contrast resulting from AFM images obtained in tapping mode to interrogate the viscoelastic behavior and...
Knowledge of the mechanical properties of electrospun fibers is important for their successful application in tissue engineering, material composites, filtration and drug delivery. In particular, electrospun collagen has great potential for biomedical applications due to its biocompatibility and promotion of cell growth and adhesion. Using a combined atomic force microscopy (AFM)/optical microscopy...
Bone is a complex and very important multi-constituent bio-composite. In this work, we focus on the arrangement of bone constituents from the nanoscopic to the microscopic scale, and investigate the influence of their arrangements on the fracture mechanisms of the whole composite. We find that bone, on the nanoscopic scale, consists of mineralized collagen fibrils held together by a non-fibrillar...
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