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The in vivo effects of inorganic mercury (Hg 2+ ) on striatal dopamine (DA) release were studied in freely moving and conscious rats using brain microdialysis techniques. Intrastriatal administration of HgCl 2 (1mM) produced an increase in extracellular DA levels of 1717±375% with respect to basal levels. This effect was attenuated in a Ca 2+ -free medium (361±66%), after pre-treatment...
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