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Human pregnancy serum and placenta are known to have the ability to degrade oxytocin (OT), the most potent uterotonic peptide. Placental leucine aminopepetidase (P-LAP), which is also called cystine aminopeptidase, is the only membrane aminopeptidase known to open the N-terminal cystine loop of OT. The soluble form of P-LAP present in maternal serum is converted from the membrane-bound form in placenta...
The transition to motherhood is arguably the most fundamental and profound stage in the lifespan of a female. The end result is an extensive transformation of the female, affecting her behaviors, emotions, and motivations. The magnitude of physiological change required to produce successful parturition cannot be underestimated. The dynamic process of pregnancy results in alterations in maternal anatomy,...
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