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Déterminer les variations d’expression des ARNm de la leptine dans les cellules mononuclées du sang (PBMC) de patients atteints de spondylarthrite ankylosante (SA) ainsi que la production de cytokines pro-inflammatoires.Vingt patients présentant une SA active ont été inclus, et l’index d’activité BASDAI et les taux de protéines de la phase aiguë ont été mesurés. L’expression des ARNm et de protéine...
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