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Simultaneous imaging of cerebral hemodynamic changes in response to functional activation during drug intoxication provides a valuable strategy to assess cocaine-induced neurovascular dysfunction. However, this requires tools with sufficient spatiotemporal resolution and an adequate signal to noise ratio (SNR). Though several technologies have been developed to address this demand during functional...
Computational fluid dynamic (CFD) based on patient-specific medical imaging data has found widespread use for visualizing and quantifying hemodynamics in cerebrovascular disease such as cerebral aneurysms or stenotic vessels. This paper focuses on optimizing mesh parameters for CFD simulation of cerebral aneurysms. Valid blood flow simulations strongly depend on the mesh quality. Meshes with a coarse...
Quantitative flow measurements with volumetric coverage and three directional flow encoding are technically feasible with magnetic resonance imaging yet prohibitively long in clinical settings. Data reconstruction from three dimensional angular undersampled MR acquisitions allows for dramatic reductions in scan time with tolerable imaging artifacts in many clinical applications. This approach provides...
The zebrafish has emerged as an excellent model organism for studies of cardiovascular development due to its optical transparency and external development during embryogenesis. However, to understand the cardiovascular structure and function beyond the early stage development requires a high-resolution, real-time, non-invasive imaging alternative due to the opacity of adult zebrafish. In this paper,...
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