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Analysis of published data shows that experimental passaging of Zaire ebolavirus (EBOV) in guinea pigs changes the risk of infection per plaque‐forming unit (PFU), increasing infectivity to some species while decreasing infectivity to others. Thus, a PFU of monkey‐adapted EBOV is 107‐fold more lethal to mice than a PFU adapted to guinea pigs. The first conclusion is that the infectivity of EBOV to...
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