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It was suggested that the years of diabetes preceding puberty may not contribute to the development of retinopathy but evidence for this is conflicting. To verify the influence of pre-pubertal diabetes, we compared the correlations between prevalence of retinopathy and diabetes duration in patients who developed type 1 diabetes before and after puberty. Six hundred and twenty-eight patients with...
It is controversial that serum lipids affect the development and progression of microvascular complications in patients with type 1 diabetes. We prospectively followed 297 patients with type 1 diabetes without end-stage renal disease for 7 years (range: 2-10). Serum lipids were measured at baseline (total and HDL-cholesterol, triglycerides and calculated LDL-cholesterol, Lipoprotein (a)). The primary...
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