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We have shown that the ameliorative effect of stannous chloride (SnCl 2 ) pretreatment on potassium dichromate (K 2 Cr 2 O 7 )-induced renal damage 24 h after K 2 Cr 2 O 7 injection was associated with the induction of heme oxygenase-1 (HO-1). In this work we evaluated: (a) if the protective effect of SnCl 2 (given 12 h before K 2...
Heme oxygenase (HO) is the rate-limiting enzyme in the degradation of heme; its inducible isozyme HO-1 protects against some types of acute tissue injury. The expression and functional role of HO-1 in rats with renal injury induced by potassium dichromate (K 2 Cr 2 O 7 ) was investigated in this work. Rats were studied 24 h after a single injection of K 2 Cr 2 ...
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