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Protein kinase C (PKC) plays a prominent role in the regulation of a variety of cellular functions, including Ca 2+ signalling. In HEK293 and Jurkat cells, the Ca 2+ release and Ca 2+ uptake stimulated by several different activators were attenuated by activation of PKC with phorbol myristate acetate (PMA) or 1-oleoyl-2-acetyl-sn-glycerol (OAG) and potentiated by PKC inhibition...
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