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Rectal gastrointestinal stromal tumors (GISTs) are uncommon, and the role of local excision versus a more extensive resection after the advent of effective targeted chemotherapy with imatinib is not known. Our aim is to present two cases of large anorectal GIST treated with local excision through a new anterolateral trans-sphincteric approach followed by adjuvant therapy with imatinib. Two patients...
Résumé Le traitement des cancers du rectum T2-3 repose en premier sur la chirurgie. Au-delà de 75 ans, la mortalité opératoire dépasse 14 %, la continence anale est souvent médiocre après résection antérieure. La radiothérapie, et notamment la radiothérapie de contact, est présentée comme une alternative à la chirurgie radicale chez les patients âgés porteurs de comorbidité et à haut risque chirurgical...
PURPOSE:. This study was designed to compare histologic T and N stages in patients with rectal adenocarcinoma undergoing various neoadjuvant radiotherapy regimens and proctectomy, in an attempt to determine if final histologic stage of the mural tumor predicts nodal status. METHODS:. Data were collected from computerized databases at two institutions on 649 consecutive patients who underwent neoadjuvant...
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