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Purpose:. The incidence of osteonecrosis of the mandibula (ON) after irradiation using modern three-dimensional planning as well as hyperfractionation or moderately accelerated irradiation has been evaluated and compared with the incidence of the preceding period. Patients and Methods:. The records of 268 head and neck cancer patients irradiated between January 1, 1980 and December 31, 1998 with a...
We analysed the incidence of a mandibular osteonecrosis (ON) in 189 patients irradiated for a cancer of the oral cavity, or of the oropharynx or epipharynx, with a total target dose of at least 60 Gy between 1980 and January 1994. Target doses per fraction were between 2.0 and 1.2 Gy, number of sessions per week was between 5 and 10, and total target doses were between 60 and 78.2 Gy. No instance...
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