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Acellular slime mould Physarum polycephalum is a popular now user-friendly living substrate for designing of future and emergent sensing and computing devices. P. polycephalum exhibits regular patterns of oscillations of its surface electrical potential. The oscillation patterns are changed when the slime mould is subjected to mechanical, chemical, electrical or optical stimuli. We evaluate feasibility...
In this position paper we propose a new approach to provide online in-vivo recordings of organ activity in real time and to overcome three major shortcuts of currently used invasive glucose sensors. In the context of diabetes, standard glucosensors recognize only glucose, whereas circulating lipids as well as amino acids are known to increase the demand in insulin and, under physiological circumstances,...
Over the past twenty-five years, silicon CMOS technology has firmly established itself as the dominant platform in the microelectronics industry. This has resulted in many recent initiatives to fabricate CMOS-based microelectrodes for the stimulation and recording of electrical activity of neurons. CMOS technology offers the potential for monolithic integration of sensors and electronics and it serves...
Conductance measurement of single ion channels and related stochastic signals is a promising technique for the development of a functional biosensor. We present results showing that silicon substrates can be used as a low noise, universal platform for recording the electrical activity of single ion channels inserted into bilayer membranes. Bilayers were suspended on polytetrafluoroethylene coated,...
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