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Animal models were developed for chronic observation with using two-photon microscopy. To demonstrate potency of the models, T-cell and macrophage migration in inguinal lymph node, spleen, abdominal cavity and kidney were observed for two weeks on single mice. The image quality was maintained high enough during an observation period to count and trace cell population and migration.
We developed an animal model for chronic observation with using two-photon microscopy. To demonstrate potency of the model, T-cell migration and proliferation in inguinal lymph node were observed for two weeks on single mice. The image quality was maintained enough high during a observation period to count and trace cell population and migration.
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