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Fe–S clusters play critical roles in cellular function throughout all three kingdoms of life. Consequently, Fe–S cluster biogenesis systems are present in most organisms. The Suf (sulfur formation) system is the most ancient of the three characterized Fe–S cluster biogenesis pathways, which also include the Isc and Nif systems. Much of the first work on the Suf system took place in Gram-negative Proteobacteria...
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