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We evaluated the renal hemodynamics and the urine protein excretion rates of 73 children with Henoch-Schönlein nephritis (HSN). In 40 children we also performed a renal biopsy. The glomerular filtration rate (GFR) and effective renal plasma flow were determined by the clearances of inulin and para-aminohippurate during water diuresis. Urine albumin and IgG excretion were assessed in short-term timed...
Proteinuria and decreased renal function are classic hallmarks of preeclampsia. The kidney, with its reliance on glomerular blood flow and glomerular barrier integrity, provides a unique window to view the preeclamptic disease process. This review briefly details the characteristic renal structural changes seen in preeclampsia and then focuses on the disordered renal hemodynamics and other determinants...
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