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Non-Invasive Glucose Monitoring devices use Multivariate Calibration (MC) methods to estimate glucose concentration in blood. The accuracy of methods depends on spectral data obtained from tongue-to-spectrometer interface. In this work we examine four widely used MC methods, they are: classical least square (CLS), inverse least square (ILS), principal component (PC) and partial least square (PLS)...
Measurements of impedance spectra used for non-invasive glucose monitoring are affected by a variety of perturbing factors such as temperature and sweat/moisture fluctuations, changes in perfusion, and body movements. In order to quantify and compensate for these perturbing effects, a multi-sensor approach was suggested. Different sensors are used, measuring signals correlated with blood glucose and...
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