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In this study, an approximate method based on a third-order polynomial equation was developed to describe diffusion - reaction model for immobilized enzyme system following reversible Michaelis-Menten kinetics in porous spherical particles. This kinetic model is used to describe glucose isomerization to fructose by the enzyme glucose isomerase. The approximate method is utilized to calculate the substrate...
A general mathematical model has been developed for predicting the performance and simulation of a packed-bed immobilized enzyme reactor performing lactose hydrolysis, which follows Michaelis–Menten kinetics with competitive product (galactose) inhibition. The performance characteristics of a packed-bed immobilized enzyme reactor have been analyzed taking into account the effects of various diffusional...
The effect of the bulk product concentration on the effectiveness factor of immobilized cell aggregates is shown to be dependent on the pattern of product inhibition experienced by the immobilized cells. If product inhibition is linear with respect to the product concentration, then the concentration of the inhibitory product in the bulk of the liquid phase is found to have no effect on the effectiveness...
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