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We investigated whether creatine (CR) and β-hydroxy-β-methylbutyrate (HMB) act by similar or different mechanisms to increase lean body mass (LBM) and strength in humans undergoing progressive resistance-exercise training. In this double-blind, 3-wk study, subjects (n = 40) were randomized to placebo (PL; n = 10), CR (20.0 g of CR/d for 7 d followed by 10.0 g of CR/d for 14 d; n = 11), HMB (3.0 g...
Elevated levels of serum creatine phosphokinase, muscular type (CK MM ) are caused primarily by diseased muscle fiber. Acute psychoses are often associated with a marked increase in serum CK MM levels, though the reason remains obscure. Since striated muscle damage is also associated with pigmenturia and myoglobinuria, we sought to determine whether the markedly high serum...
Background: Elevated serum creatine phosphokinase (CP-K) MM level is frequently found in acute psychosis. Theories relate this CPKemia to psychomotor agitation and medication. We hypothesized that psychosis-related CPKemia observed in individual patients is relatively consistent.Methods: Ninety psychotic patients were studied; 83% were schizophrenics (Brief Psychiatric Rating Scale...
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