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5-FU/Megestrol acetate loaded fibrinogen-graft-PNIPAAm Nanogels (5-FU/Meg-fib-graft-PNIPAAm NGs) were prepared for thermo responsive drug delivery toward α 5 β 1 -integrins expressing breast cancer cells in vitro (MCF-7 cells). The 60–100nm sized fib-graft-PNIPAAm nanogels (LCST=35°C) were prepared by CaCl 2 cross-linker. 5-FU/Meg-fib-graft-PNIPAAm NGs showed particle size...
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