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The astrocytic water channel proteins aquaporin 1 (AQP1) and aquaporin 4 (AQP4) are known to be altered in brains affected by several neurodegenerative disorders, including Alzheimer's disease. However, AQP expression in brains affected by Parkinson's disease (PD) has not been described in detail. Recently, it has been reported that α‐synuclein (α‐syn)‐immunolabeled astrocytes show preferential distribution...
We report two unusual autopsy cases with frontotemporal lobar degeneration (FTLD) that were hyperphosphorylated‐tau‐ and TAR DNA binding protein 43 (TDP‐43)‐ negative. The behavioral symptoms in both cases were compatible with frontotemporal dementia, but they exhibited more prominent speech and language related symptoms than previously reported. Moreover, they displayed a short duration of the disease;...
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