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Peptide nucleic acid (PNA) is a unique combination of peptides and nucleic acids. PNA can exhibit hydrogen bonding interactions with complementary nucleobases like DNA/RNA. Also, its polyamide backbone allows easy incorporation of biomolecules like peptides and proteins to build hybrid molecular constructs. Because of chimeric structural properties, PNA has lots of potential to build diverse nanostructures...
The unique optical and electronic properties of living systems are impressive. Peptide‐based supramolecular self‐assembly systems attempt to mimic these properties by preparation optical/electronic function materials with specific structure through simple building blocks, rational molecular design, and specific kinetic stimulation. From the perspective of building blocks and assembly strategies, the...
Phase‐Change Peptide Nanoemulsions
Real‐time monitoring of immune cells in tissues holds promise to improve disease diagnosis and therapy. In article number 2301673, Scott H. Medina and co‐workers report the ultrasound imaging of macrophages in situ using phase‐changing peptide nanoemulsions. After phagocytosis, the emulsion contrast agent can be converted into echogenic bubbles to enable precise...
Macrophages are specialized phagocytes that play central roles in immunity and tissue repair. Their diverse functionalities have led to an evolution of new allogenic and autologous macrophage products. However, realizing the full therapeutic potential of these cell‐based therapies requires development of imaging technologies that can track immune cell migration within tissues in real‐time. Such innovations...