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The experiment was performed on rats that were given ethanol ad libitum for 4 weeks. After decapitation of the animals, pancreatic sections were prepared for an electron microscopy. A significant broadening of the rough endoplasmic reticulum cisterns in the vesicular cells was observed as well as the presence of nuclei with irregular outlines resulted from placation of the nuclear membrane, which...
In order to explore the morphological basis of the altered feeding behaviour of old rats, an ultrastructural investigation of the magnocellular neurons of the hypothalamic paraventricular nucleus (PVN) was performed. Young and old male Wistar rats, 5 and 24 months old, respectively, and with each age group comprising 12 animals, were divided into 3 groups. The rats in Group I were used as controls...
Many hypothalamic nuclei are involved in the regulation of food intake and energy homeostasis. An ultrastructural investigation of the hypothalamic ventromedial nucleus (VMN), a hypothetical “satiety centre” was performed to explore the morphological basis of altered feeding behaviour of old rats in an experimental model of fasting/refeeding. Young (5 months old, n = 12) and old (24 months old, n...
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