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There are strong implications that Amyloid beta (Aβ) peptide causes neurotoxicity in Alzheimer's disease (AD) through (i) pore formation, (ii) the disruption of ionic channels that could affect calcium homeostasis, and (iii) receptor binding. The actual mechanism(s) remains unclear. In this study, we utilised cell-sized model membranes to observe the stability of lipid vesicles, in real-time, in the...
Quick and accurate response to the relief demand is vital to an emergency logistics network under disaster spreading. In this paper, we first characterize the disaster spreading process to forecast the time-varying relief demand, by using an epidemic model to analyze the relationships among three groups of affected individuals. Then, a new three-tiered emergency logistics network equilibrium model...
Communication between cells in multicellular organisms such as animals, humans and plants is essential for co-ordinating the organismic activities of fertilization, growth, survival and reproduction. This bio-chemical communication between trillions of cells in organisms can be more complex than the Internet. This paper develops a CMOS circuit model of signal reception and signal transduction within...
The optical anisotropy of alive eye cornea has the photoelastic nature and is caused by stretching action of oculomotor muscles and intraocular pressure. In this paper, the results of eye tensely-deformed conditions model for using in differential diagnostics of oculomotor muscles pathology are presented
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