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article

Corticospinal fibers with different origins impair in amyotrophic lateral sclerosis: A neurite orientation dispersion and density imaging study

Nao‐Xin Huang, Wen Qin, Jia‐Hui Lin, Qiu‐Yi Dong, more

CNS Neuroscience & Therapeutics > 29 > 11 > 3406 - 3415

Aims To investigate microstructural impairments of corticospinal tracts (CSTs) with different origins in amyotrophic lateral sclerosis (ALS) using neurite orientation dispersion and density imaging (NODDI). Methods Diffusion‐weighted imaging data acquired from 39 patients with ALS and 50 controls were used to estimate NODDI and diffusion tensor imaging (DTI) models. Fine maps of CST subfibers originating...

article

Fiber orientation distribution from diffusion MRI: Effects of inaccurate response function calibration

Fenghua Guo, Chantal M. W. Tax, Alberto De Luca, Max A. Viergever, more

Journal of Neuroimaging > 31 > 6 > 1082 - 1098

Background and Purpose Diffusion MRI of the brain enables to quantify white matter fiber orientations noninvasively. Several approaches have been proposed to estimate such characteristics from diffusion MRI data with spherical deconvolution being one of the most widely used methods. Spherical deconvolution requires to define––or derive from the data––a response function, which is used to compute...

article

SuperDTI: Ultrafast DTI and fiber tractography with deep learning

Hongyu Li, Zifei Liang, Chaoyi Zhang, Ruiying Liu, more

Magnetic Resonance in Medicine > 86 > 6 > 3334 - 3347

Purpose To develop a deep learning–based reconstruction framework for ultrafast and robust diffusion tensor imaging and fiber tractography. Methods SuperDTI was developed to learn the nonlinear relationship between DWIs and the corresponding diffusion tensor parameter maps. It bypasses the tensor fitting procedure, which is highly susceptible to noises and motions in DWIs. The network was trained...

article

Evaluation of the female bladder neck and urethra using MRI with fiber tractography: Prospective study on a large cohort of continent women

Catherine Roy, Mickael Ohana, Aissam Labani, Thibault Tricard, more

Neurourology and Urodynamics > 40 > 6 > 1441 - 1449

Aims To prospectively evaluate the performance of a last generation magnetic resonance imaging (MRI) device with tractography to identify the normal female urethral sphincters in terms of morphology and quantification on a large cohort of continent women. Methods We have recorded the data of 75 continent women who underwent a diffusion tensor imaging (DTI) sequence with fiber tractography during...

article

JEDI: Joint Estimation Diffusion Imaging of macroscopic and microscopic tissue properties

Lawrence R. Frank, Benjamin Zahneisen, Vitaly L. Galinsky

Magnetic Resonance in Medicine > 84 > 2 > 966 - 990

Purpose A new method for enhancing the sensitivity of diffusion MRI (dMRI) by combining the data from single (sPFG) and double (dPFG) pulsed field gradient experiments is presented. Methods This method uses our JESTER framework to combine microscopic anisotropy information from dFPG experiments using a new method called diffusion tensor subspace imaging (DiTSI) to augment the macroscopic anisotropy...

article

Diffusion Tensor Imaging (DTI) of the Cesarean‐Scarred Uterus in vivo at 3T: Comparison Study of DTI Parameters Between Nonpregnant and Pregnant Cases

Wenting Zhang, Juan Chen

Journal of Magnetic Resonance Imaging > 51 > 1 > 124 - 130

Background Fiber architecture of the human uterus can be depicted in vivo using 3T MR‐DTI (diffusion tensor imaging). Purpose To investigate the differences in fibrous structure and DTI‐related parameters between nonpregnant and pregnant cases in vivo. Study Type Prospective case–control study. Subjects Thirty‐one subjects were divided into two groups; 18 nonpregnant volunteers with previous...

article

Volumetric assessment of spontaneous mechanical activities by simultaneous multi‐slice MRI techniques with correlation to muscle fiber orientation

Martin Schwartz, Petros Martirosian, Günter Steidle, Michael Erb, more

NMR in Biomedicine > 31 > 11 > n/a - n/a

The purpose of this work was assessment of volumetric characteristics of spontaneous mechanical activities in musculature (SMAMs) by diffusion‐weighted simultaneous multi‐slice (DW‐SMS) imaging and spatial correlation to anatomical structure, as revealed by fusion to fiber tractographic information derived from diffusion‐tensor imaging (DTI). The feasibility of using DW‐SMS to image spontaneous events...

article

Multicenter reproducibility study of diffusion MRI and fiber tractography of the lumbosacral nerves

Wieke Haakma, Jeroen Hendrikse, Lars Uhrenholt, Alexander Leemans, more

Journal of Magnetic Resonance Imaging > 48 > 4 > 951 - 963

Background Diffusion tensor imaging (DTI) has been applied in the lumbar and sacral nerves in vivo, but information about the reproducibility of this method is needed before DTI can be used reliably in clinical practice across centers. Purpose In this multicenter study the reproducibility of DTI of the lumbosacral nerves in healthy volunteers was investigated. Study Type Prospective control series...

article

Diffusion tensor imaging (DTI) and Tractography of the spinal cord in pediatric population with spinal lipomas: preliminary study

Pierre Antherieu, R. Levy, T. Saint Denis, L. Lohkamp, more

Child's Nervous System > 2019 > 35 > 1 > 129-137

Purpose Diffusion tensor imaging (DTI) allows studying the micro and macro architecture. One of the major challenges in dysraphism is to know the morphologic organization of the spinal cord. In a preliminary work, spinal lipoma was chosen for analyzing the micro-architecture parameters and fiber morphology of the spinal cord by DTI with tractography. Methods Twelve patients (0–8 years) related to...

article

Robust Identification of Rich-Club Organization in Weighted and Dense Structural Connectomes

Xiaoyun Liang, Chun-Hung Yeh, Alan Connelly, Fernando Calamante

Brain Topography > 2019 > 32 > 1 > 1-16

The human brain is a complex network, in which some brain regions, denoted as ‘hub’ regions, play critically important roles. Some of these hubs are highly interconnected forming a rich-club organization, which has been identified based on the degree metric from structural connectomes constructed using diffusion tensor imaging (DTI)-based fiber tractography. However, given the limitations of DTI,...

article

Generalized q-sampling imaging fiber tractography reveals displacement and infiltration of fiber tracts in low-grade gliomas

Pinar Celtikci, David T. Fernandes-Cabral, Fang-Cheng Yeh, Sandip S. Panesar, more

Neuroradiology > 2018 > 60 > 3 > 267-280

Purpose Low-grade gliomas (LGGs) are slow growing brain tumors that often cause displacement and/or infiltration of the surrounding white matter pathways. Differentiation between infiltration and displacement of fiber tracts remains a challenge. Currently, there is no reliable noninvasive imaging method capable of revealing such white matter alteration patterns. We employed quantitative anisotropy...

article

Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord

Mahdi Alizadeh, Joshua Fisher, Sona Saksena, Yusra Sultan, more

NeuroImage: Clinical > 2018 > 18 > C > 784-792

Diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) are two techniques that can measure white matter integrity of the spinal cord. Recently, DTI indices have been shown to change with age. The purpose of this study is (a) to evaluate the maturational states of the entire pediatric spinal cord using DTI and DTT indices including fractional anisotropy (FA), mean diffusivity (MD),...

article

Diffusion tensor imaging of the anterior cruciate ligament graft

Pieter Van Dyck, Martijn Froeling, Eline De Smet, Pim Pullens, more

Journal of Magnetic Resonance Imaging > 46 > 5 > 1423 - 1432

Purpose A great need exists for objective biomarkers to assess graft healing following ACL reconstruction to guide the time of return to sports. The purpose of this study was to evaluate the feasibility and reliability of diffusion tensor imaging (DTI) to delineate the anterior cruciate ligament (ACL) graft and to investigate its diffusion properties using a clinical 3T scanner. Materials and Methods...

article

MultiXplore: Visual exploration platform for multimodal neuroimaging data

Saeed M. Bakhshmand, Ali R. Khan, Sandrine de Ribaupierre, Roy Eagleson

Journal of Neuroscience Methods > 2017 > 290 > C > 1-12

Construction of brain functional and structural networks by neuroimaging methods facilitates inter-modal studies. These type of studies often demand exploration tools to carry out functional–structural discoveries and answer questions regarding the anatomical basis of brain networks.This paper describes the design and development of a software module for interactive visualization and exploration of...

article

Fiber tractography using machine learning

Peter F. Neher, Marc-Alexandre Côté, Jean-Christophe Houde, Maxime Descoteaux, more

NeuroImage > 2017 > 158 > C > 417-429

We present a fiber tractography approach based on a random forest classification and voting process, guiding each step of the streamline progression by directly processing raw diffusion-weighted signal intensities. For comparison to the state-of-the-art, i.e. tractography pipelines that rely on mathematical modeling, we performed a quantitative and qualitative evaluation with multiple phantom and...

article

Stability metrics for optic radiation tractography: Towards damage prediction after resective surgery

Stephan Meesters, Pauly Ossenblok, Louis Wagner, Olaf Schijns, more

Journal of Neuroscience Methods > 2017 > 288 > C > 34-44

An accurate delineation of the optic radiation (OR) using diffusion MR tractography may reduce the risk of a visual field deficit after temporal lobe resection. However, tractography is prone to generate spurious streamlines, which deviate strongly from neighboring streamlines and hinder a reliable distance measurement between the temporal pole and the Meyer's loop (ML-TP distance).Stability metrics...

article

White matter microstructure in children with autistic traits

Laura M.E. Blanken, Ryan L. Muetzel, Vincent W.V. Jaddoe, Frank C. Verhulst, more

Psychiatry Research: Neuroimaging > 2017 > 263 > C > 127-134

Autism spectrum disorder (ASD) is thought to arise from aberrant development of connections in the brain. Previous studies have identified differences in white matter microstructure in children with ASD, offering support to such hypotheses. While ASD is thought to represent the severe end of a spectrum of traits, there are no studies evaluating white matter microstructure in relation to autistic traits...

article

Semi-local tractography strategies using neighborhood information

Helen Schomburg, Thorsten Hohage

Medical Image Analysis > 2017 > 38 > C > 165-183

Fiber tractography based on Diffusion MRI measurements is a valuable tool for the detection and visual representation of neural pathways in vivo. We present a novel fiber orientation distribution function (ODF) based streamline tractography approach which incorporates information of neighboring regions derived from a Bayesian model. In each iteration step, the proposed algorithm defines a set of candidate...

chapter

Hessian matrix-based structure tensor analysis for fiber enhancement and direction encoding

Shangbin Chen, Xiangning Li, Anan Li, Jie Peng, more

2nd IET International Conference on Biomedical Image and Signal Processing (ICBISP 2017) > 1 - 5

2nd IET International Conference on Biomedical Image and Signal Processing (ICBISP 2017)

Neuroanatomical connectivity is crucial for understanding brain functions and diseases. Quantitative analysis of fiber orientation and structural connectivity at single axon resolution has led to great challenges. To address this issue, Hessian matrix based structure tensor (HST) has been introduced for quantifying fiber architecture. Optimized parameters and block based processing pipeline has enabled...

article

The importance of correcting for signal drift in diffusion MRI

Sjoerd B. Vos, Chantal M. W. Tax, Peter R. Luijten, Sebastien Ourselin, more

Magnetic Resonance in Medicine > 77 > 1 > 285 - 299

Purpose To investigate previously unreported effects of signal drift as a result of temporal scanner instability on diffusion MRI data analysis and to propose a method to correct this signal drift. Methods We investigated the signal magnitude of non‐diffusion‐weighted EPI volumes in a series of diffusion‐weighted imaging experiments to determine whether signal magnitude changes over time. Different...

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FIBER TRACTOGRAPHY (84)
DIFFUSION TENSOR IMAGING (45)
WHITE MATTER (13)
DTI (10)
BRAIN (9)
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CORTICOSPINAL TRACT (2)
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Corticospinal fibers with different origins impair in amyotrophic lateral sclerosis: A neurite orientation dispersion and density imaging study

Fiber orientation distribution from diffusion MRI: Effects of inaccurate response function calibration

SuperDTI: Ultrafast DTI and fiber tractography with deep learning

Evaluation of the female bladder neck and urethra using MRI with fiber tractography: Prospective study on a large cohort of continent women

JEDI: Joint Estimation Diffusion Imaging of macroscopic and microscopic tissue properties

Diffusion Tensor Imaging (DTI) of the Cesarean‐Scarred Uterus in vivo at 3T: Comparison Study of DTI Parameters Between Nonpregnant and Pregnant Cases

Volumetric assessment of spontaneous mechanical activities by simultaneous multi‐slice MRI techniques with correlation to muscle fiber orientation

Multicenter reproducibility study of diffusion MRI and fiber tractography of the lumbosacral nerves

Diffusion tensor imaging (DTI) and Tractography of the spinal cord in pediatric population with spinal lipomas: preliminary study

Robust Identification of Rich-Club Organization in Weighted and Dense Structural Connectomes

Generalized q-sampling imaging fiber tractography reveals displacement and infiltration of fiber tracts in low-grade gliomas

Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord

Diffusion tensor imaging of the anterior cruciate ligament graft

MultiXplore: Visual exploration platform for multimodal neuroimaging data

Fiber tractography using machine learning

Stability metrics for optic radiation tractography: Towards damage prediction after resective surgery

White matter microstructure in children with autistic traits

Semi-local tractography strategies using neighborhood information

Hessian matrix-based structure tensor analysis for fiber enhancement and direction encoding

The importance of correcting for signal drift in diffusion MRI

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