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The vagus nerve (VN), the longest nerve of the organism innervating the gastrointestinal tract, is a mixed nerve with anti‐inflammatory properties through its afferents, activating the hypothalamic–pituitary adrenal axis, and its efferents through the cholinergic anti‐inflammatory pathway inhibiting the release of pro‐inflammatory cytokines (e.g., TNFα) by splenic and gut macrophages. In addition,...