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This work presents a new systematic approach to design impedance measurement systems for living cell detection and monitoring. The hardware of the system was implemented in PCBs as a proof-of-concept. A DAC channel generates the required excitation signals to be applied onto the living cell and the current flowing through the cell is converted into voltage and digitized by an ADC channel. An FPGA...
In this contribution a novel biosensor system for the on-line analysis of stimulated neuronal cells embedded in gel matrices is presented. The system enables electrical impedance measurement of gel films in the range of 10 to 110 MHz, while cell culture medium is continuously flowing in parallel to the sensor surface. A technique for the immobilization of cells in bactoagar and the fabrication of...
An impedance based electrochemical biosensor was designed and fabricated for the detection of various chemical and biological species, with glass as substrate material and gold electrodes. A flow cell with inlet and outlet ports for the micro fluidic chamber was designed and fabricated using an acrylic material with a reservoir volume of 78 ??l. The feasibility of the fabricated sensor for detecting...
Differentiation of normal human bladder cell (SVHUC) between two different-grade bladder cancer cell lines (TSGH8301, grade II and TCCSUP, grade IV) was successful developed based on a dielectrophoresis (DEP) microchip with microcavity array and multilayer electrodes. Single cell could be firstly trapped in the microcavity by negative DEP force between top and middle electrodes without overlapping...
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