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In this study, we investigated optical performance of a biosensor based on the phenomenon of localized surface plasmon resonance (LSPR) in spherical Au nanoparticles, covered by a dense monolayer of globular biomolecules. Theoretical approaches used include Mie theory for a coated spherical particle, electron relaxation time correction for nanoparticle's optical constants, and symmetrical Bruggeman...
A 10 nm nanogold particle was used to label monoclone CEA antibody to prepare an immunonanogold resonance scattering probe (AuCEAAb) for detection of CEA. In the pH 6.8 Na2HPO4-NaH2PO4 buffer solution and in the presence of PEG-6000, the immunoreaction between CEA and AuCEAAb took place to form the immunonanogold complex that can be removed by centrifugation technique. The supernatant containing AuCEAAb...
In this paper, we present a new compact coupled double layer hybrid plasmonic system based on metal nano-strips arrays. We demonstrate the feasibility of this device as a platform for biophotonic applications by means of modal analysis and two-dimensional (2D) finite-difference time-domain (FDTD). With the resonant condition being satisfied, the metal nano-strips behave as optical resonators and antennas...
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