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The ordered electrical stimulation of the ventricles is achieved by a specialized network of fibres known as the Purkinje system. The gross anatomy and basic functional role of the Purkinje system is well understood. However, very little is known about the detailed anatomy of the Purkinje system, its inter-individual variability and the implications of the variability in ventricular function, in part...
The role of the 3D infarct structure in arrhythmia generation and maintenance in hearts with myocardial infarction cannot be fully elucidated through experimental techniques alone. Our aim was to develop methodology to construct a high resolution computational model of the infarcted canine heart using magnetic resonance (MRI) and diffusion tensor images (DTI) and then to use the resulting model to...
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