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The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring copy number aberrations are recognized to be important in cancer as they influence multiple genes on a global scale. The challenge in detecting trans-effects is mainly due to the computational difficulty...
The primary objective of disparities research is to model the differences across multiple groups and identify the groups that behave significantly different from each other. Independently generating various decision trees for different subsets of the data will not allow us to study the impact of the various attributes on these different subgroups. We propose a novel technique for inducing similar...
In this paper, we present a novel technique of building hybrid decision support systems which integrates traditional decision support systems with agent based models for use in breast cancer analysis for better prediction and recommendation. Our system is based on using queries from data (converted to a standardized electronic template) to provide for simulation variables in an agent-based model....
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