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Quanterix and Stratec Biomedical have developed an automated analyzer that enables the measurement of subfemtomolar concentrations of proteins. The development of this technology focusing on the custom optical module and microfluidic disc is outlined below.
Microfluidic technologies have become increasingly effective for diagnostic, physiological, and biochemical applications. The biocompatibility of MEMS devices, which are evolving rapidly in their practicality, has become the paramount property to investigate and optimize through biological and optical testing. Potential applications comprise cell culture, biosensing, immunoisolation, bioparticle sorting,...
Microfluidic channels containing protein micropatterned surfaces are useful in many bioanalytical and biological applications. In this study, we developed a new method to integrate microfluidics and protein micropatterning by attaching poly(dimethylsiloxane) (PDMS) microfluidic channels to bio-friendly photoresist films via poly(dopamine) (PDA) adhesive. A bio-friendly photoresist poly(2,2-dimethoxy...
In this study, we demonstrate the formation of 3D cell-adhesive hydrogels exhibiting well-defined spatial variation in stiffness using our previously developed microfluidics-based lithography technique. PEG monoacrylate-linked bovine fibrinogen (PEG-fibrinogen) is photopolymerized into specific, user-defined shapes inside a microchannel, and successive cycles of fabrication result in a heterogeneous...
In this report, we will present a novel liposome handling method on microfluidic channel. For the quantitative analysis of individual giant liposomes, a microfluidic device with multi-pillar was designed. Liposomes suspension from neutral phospholipids prepared by natural swelling method was introduced into the separation device. As a result, giant liposomes are safely trapped in the microscope view...
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