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Discovering similar diseases is very helpful for revealing the pathogenesis of diseases and making direction in drug use. And related diseases are often triggered by disease-related genes. Therefore, function interaction networks structured by disease-related genes are suitable for measurement of disease similarity, and some methods have utilized the advantage of function interaction of disease-related...
Disease comorbidity is the presence of one or more diseases along with a primary disorder, which causes additional pain to patients and leads to the failure of standard treatments compared with single diseases. Therefore, the identification of potential comorbidity can help prevent those comorbid diseases when treating a primary disease. Unfortunately, most of current known disease comorbidities are...
Similar diseases are often caused by their similar molecular origins, such as disease-related protein-coding genes (PCGs). And nowadays, the function of PCGs has been widely studied on a gene function network, where each node represents a gene and each edge indicates an interaction between pair-wise genes. Therefore, functional interaction between disease-related PCGs should be exploited to measure...
Glaucoma is a silent eye disease that steals sight without warning and it is the second leading cause of blindness worldwide. It cannot be cured but it can be controlled. A gene network analysis to understand the cross talk between glaucoma networks of genes could contribute to better understanding and treatment of the disease. In this paper, we extend our previous text mining and network analysis...
In the past years, organizations worldwide have put many efforts in establishing guidelines for the medical practice. However, it has become clear that in order to improve patient care it is necessary to check and ensure the adherence to the established guidelines. Therefore, in 2007, the Dutch Society of Cardiology (NVVC) has implemented a structure for national databases that will serve as benchmark...
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